This book provides a comprehensive overview of Typhoid Fever, covering its causes, pathogenesis, diagnosis, treatment, and prevention. Chapter 1 introduces the reader to the disease, its three Salmonella antigens, and its epidemiology and spread. Chapter 2 explains how the disease spreads and affects individuals, highlighting its symptoms and risk factors. Chapter 3 delves into the diagnostic process and available methods, such as blood culture and the Widal test. Chapter 4 covers the various treatments for Typhoid Fever, including antibiotics and supportive care. Chapter 5 explores different prevention methods and their effectiveness, such as vaccination and identifying high-risk areas. Chapter 6 focuses on supportive care, including when antibiotics are needed, how to take them properly, and potential side effects. Chapter 7 describes different types of antibiotics that can be used to treat Typhoid Fever, including penicillins and fluoroquinolones. Chapter 8 explains management options for home care and hospital treatment and addresses complications and long-term care. Finally, Chapter 9 discusses the possible complications of Typhoid Fever, such as perforation and peritonitis, and the importance of health education for patients. This book is an essential resource for anyone seeking to understand and manage Typhoid Fever.